Manufacturing Setup at Punagri
Experience excellence in pharmaceutical development and manufacturing with Punagri
Punagri is a leading provider of Contract Development and Manufacturing (CDMO) services in India that provides quality pharmaceutical development and manufacturing solutions. Our commitment to innovation and customer satisfaction has made us one of the top-rated CDMO pharma companies in India, with complete, trustworthy, and scalable Pharma Intermediate development and manufacturing solutions.
Our CDMO services cover the entire Pharma Intermediate development life cycle. From initial concept through commercialization, we help clients in creating new products and manufacturing on a larger scale to satisfy increasing market demand. Our trained professionals guarantee that each product meets the highest level of quality and safety.
Floor Plan & Site Plan
![PPT_pages-to-jpg-0004[1]](https://punagri.com/wp-content/uploads/2025/05/PPT_pages-to-jpg-00041.jpg)
This is the typical floor plan of the Plant building (Ground + 4 floors)
• Area marked in yellow is vacant to accommodate equipment for future expansion or contract manufacturing requirements
This is the typical floor plan of the Plant building (Ground + 4 floors)
![PPT_pages-to-jpg-0003[1]](https://punagri.com/wp-content/uploads/2025/05/PPT_pages-to-jpg-00031.jpg)
MULTI PRODUCT PLANT (MPP)
EQUIPMENT : SS-316 Reactors
| EQUIPMENT CAPACITY | AGITATOR DETAILS | OPERATING CONDITION |
|---|---|---|
| 4000 L x 1 Nos | Pitch Blade Turbine with a Tickler in the bottom | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| 5000 L x 1 Nos | Anchor | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| 6000 L x 5 Nos | Anchor & Turbine with a Tickler in the bottom | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| 8000 L x 2 Nos | Pitch Blade & Anchor | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
EQUIPMENT : MSGL Reactors
| EQUIPMENT CAPACITY | AGITATOR DETAILS | OPERATING CONDITION |
|---|---|---|
| 1600 L x 2 Nos | Anchor & Retreat Curved Blade | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| 3000 L x 2 Nos | Anchor & Retreat Curved Blade | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| **3000 L x 1 Nos | Pitch Blade Turbine + Impeller | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| 5000 L x 1 Nos | Anchor | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| 6300 L x 3 Nos | Anchor & Retreat Curved Blade | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
| 8000 L x 2 Nos | Anchor & Retreat Curved Blade | Pressure : Full Vacuum to 5 Kg / cm² g Temp : -20 to 130 C |
• All Reactors are provided with Cooling water, Chilled Water, Brine, Hot Water, Steam, Nitrogen Blanketing, Vacuum 5.0 Torr
• All Reactors have Primary and Secondary condensers with Cooling Water & Chilled Water as utilities respectively
• Reactor marked with ** has limpet designed at 15 kg/cm²g pressure. All other Reactor Jackets or limpets are designed at 6 kg/cm²g pressure
FILTERS
| EQUIPMENT | NUMBER OF IDENTICAL EQUIPMENT | EQUIPMENT SIZE / CAPACITY |
|---|---|---|
| Centrifuge SS-316 | 1 | 60'' |
| Centrifuge SS-ETFE | 3 | 60'' |
| Sparkler Filter SS-316 | 2 | 18" x 15 Plate |
| Inline Filter SS-316 | 6 | 5 m³/hr |
| Inline Filter SS-304/PTFE | 2 | 5 m³/hr |
DRYERS
| Agitated Nutch Filter Dryer SS-316 | 2 | 5000 L (Filtration area: 5 m²) |
|---|---|---|
| Vertical Conical Dryer SS-316 | 1 | 2000 L |
| Spherical Dryer SS-316 | 1 | 2000 L |
| Spherical Dryer Hastelloy C-22 | 1 | 400 L |
MINI PRODUCT PLANT
EQUIPMENT : SS-316 Reactors
| EQUIPMENT CAPACITY | OPERATING CONDITION |
|---|---|
| 100 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
| 250 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
| 630 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
| 1000 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
EQUIPMENT : MSGL Reactors
| EUIPMENT CAPACITY | OPERATING CONDITION |
|---|---|
| 100 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
| 250 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
| 630 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
| 1000 L | Pressure: Full Vacuum to 8 kg/cm²g, Temp: -20 to 130°C |
• All Reactors are provided with Cooling water, Chilled Water, Brine, Hot Water, Steam, Nitrogen Blanketing, Vacuum 5.0 Torr
• All Reactors have Primary condensers with Chilled Water as utility
• All Reactors Jackets or Limpets are designed at 6 kg/cm²g pressure
FILTERS
| EQUIPMENT | Equipment Size/Capacity |
|---|---|
| Centrifuge SS-316 | 24" x 1 Nos |
| Centrifuge SS-304/ETFE | 24" x 1 Nos |
| Sparkler Filter SS-304 | 2 m³/hr x 1 Nos |
| Inline Filter SS-316 | 2 m³/hr x 1 Nos |
| Inline Filter SS-304/PTFE | 2 m³/hr x 1 Nos |
DRYERS
| Equipment | Equipment Size/Capacity |
|---|---|
| Agitated Nutch Filter Dryer SS-316 | 250 L x 1 Nos |
| Vertical Conical Dryer SS-316 | 200 L x 1 Nos |
GMP EQUIPMENT
| Equipment | Equipment Size/Capacity |
|---|---|
| Reactor SS-316 | 250 L x 1 Nos |
| Reactor MSGL | 250 L x 1 Nos |
| Centrifuge SS-304/ETFE | 24" x 1 Nos |
| Vertical Conical Dryer Hastelloy C-22 | 75 L x 1 Nos |
• Classified Area: Clean Room, ISO Class-8
HYDROGENATION PLANT
HYDROGENATORS
| Equipment | Equipment Capacity | Operating Condition |
|---|---|---|
| Hydrogenator Reactor SS-316 with Catalyst filter | 250 L x 1 Nos | Pressure: Full Vacuum to 50 kg/cm²g, Temp: -20 to 130°C |
| Hydrogenator Reactor SS-316 with Catalyst filter | 5000 L x 2 Nos | Pressure: Full Vacuum to 25 kg/cm²g, Temp: -20 to 130°C |
ANCILLARY VESSELS
| Equipment | Equipment Capacity |
|---|---|
| Solution Preparation Vessel SS-316 | 5000 L x 1 Nos |
| Solution Preparation Vessel SS-316 | 7000 L x 1 Nos |
| Solvent Charging Vessel SS-316 | 2000 L x 2 Nos |
| Catalyst Charging Vessel SS-316 | 250 L x 2 Nos |
| Filtrate Hold Vessel SS-316 | 5000 L x 1 Nos |
| Filtrate Hold Vessel SS-316 | 7000 L x 1 Nos |
| Catch Pot MS | 8000 L x 1 Nos |
UTILITIES
| Equipment | No. of Identical Equipment | Equipment/Capacity |
|---|---|---|
| Process Cooling Tower PP/FRP | 1 | 1500 TR |
| Utility Cooling Tower PP/FRP | 1 | 750 TR |
| Cooling Tower for Condensate PP/FRP | 1 | 200 TR |
| Chilled Water Plant MS | 2 | 143 TR (@7°C) |
| Chilled Brine Plant MS | 2 | 43 TR (@-20°C) |
| Boiler CS | 1 | 8000 kg/hr (@9.5 kg/cm²g) |
| Chimney MS | 1 | 8000 kg/hr |
| Hot Water Systems | 3 | 60000 kcal/hr (@-90°C) |
| Hot Water System | 1 | 400000 kcal/hr (@-90°C) |
| Oil Heating Cooling System | 1 | 80000 kcal/hr (@10 to 120°C) |
| Dry Vacuum Pumps | 5 | 200 m³/hr (10 torr) |
| Water Jet Ejectors SS-316 | 4 | 120 m³/hr (40 torr) |
| Water Jet Ejectors Graphite | 2 | 120 m³/hr (40 torr) |
| Steam + Water Jet two stage Ejector | 1 | 300 m³/hr (10 torr) |
| 4 Stage Steam Jet Ejector | 1 | 2000 m³/hr (1 torr) |
| Instrument Air CS | 2 | 500 nm³/hr (-40 PDP) |
| Nitrogen Plant CS | 1 | 50 nm³/hr (99.5%) |
| Process Water Plant SS-316 | 1 | 20 m³/hr |
| Transformer | 2 | 2000 KVA |
| DG | 1 | 1010 KVA |
- Primary Steam Supply from external vendor having coal & briquets fired boiler with inhouse gas fired boiler
for alternate steam supply
DCS
• Yokogawa DCS system
• Automized Hydrogenation
• Empower server system for quality lab instruments
TANK FARM
| Equipment | Equipment Capacity |
|---|---|
| Storage Tank SS-304 | 25,000 L x 2 Nos |
| Storage Tank SS-316 | 25,000 L x 4 Nos |
| Storage Tank MSGL | 25,000 L x 3 Nos |
| Storage Tank MS | 25,000 L x 4 Nos |
| Scrubber Tank PP/FRP | 5,000 L x 1 Nos |
| Storage Tank PP/FRP | 50,000 L x 4 Nos |
ETP
| EQUIPMENT | EQUIPMENT CAPACITY | MOC |
|---|---|---|
| Scrubber Column (Alkali Scrubber) | 200 kg/hr | PP/FRP |
| Scrubber Column (Acidic Scrubber) | 150 kg/hr | PP/FRP |
| EQUIPMENT / SYSTEM | EQUIPMENT CAPACITY | TREATMENT METHOD |
|---|---|---|
| High TDS, High COD Treatment System | 76 KLD | Primary Treatment + Stripping + Evaporation by (MVR-Evaporator + ATFD) + Tertiary Treatment |
| Moderate TDS, Low/Moderate COD Treatment System | 68 KLD | Primary + Secondary + Tertiary Treatment |
| Low TDS, No COD Treatment System | 59 KLD | Primary Treatment + Tertiary Treatment |
Ancillary Facilities
- Underground Storage Tank Facility for Class 'A' Solvents.
- Automated plant run by a Distributed Control System (DCS), ensuring consistent quality and reliable data.
- Three Stage Ejector (1 Torr), High Vacuum Pump (0.5 Torr), Scrubbers for SO₂, SO₃, NH₃, HCl.
- 185 KLD Effluent Treatment Plant (ZLD) with Solvent Stripper, Evaporator System, Biological Treatment, Reverse Osmosis Plant.
- Utilities with active standbys and contingency planning.
Current Site Photos
Production Infrastructure
Production Scale Facility
| PLANNED KEY EQUIPMENT | CAPACITY | TIME RANGE | PRESSURE RANGE |
|---|---|---|---|
|
SS316 Reactors MSGL Reactors |
2KL-10KL 2KL-10KL |
-25 to 180°C -25 to 200°C |
FV to 6 Kg/cm² FV to 6 Kg/cm² |
|
SS316 Hydrogenators |
250 L & 5KL |
-25 to 250 C |
FV to 50 Kg/cm² |
|
SS-ETFE, SS316, MSRL. Centrifuges |
60″ |
-20 to 120 °C |
ATM |
|
Agitated Nutsche Filter & Dryer (SS316) |
5KL |
-25 to 180°C |
FV to 6 Kg/cm² |
|
Rotary Cone Vacuum Dryer (SS316)
Rotary Vacuum Paddle D Dryer (SS316) Vacuum Tray Dryer (SS316) Tray Dryer (SS316) Fluidized Bed Dryer (SS316) |
3KL 3KL 48 Trays 96 Trays 250 L |
150°C 150°C 150°C 150°C 150°C |
FV to ATM FV to ATM FV to ATM ATM ATM |
Pilot Scale Facility
| PLANNED KEY EQUIPMENT | CAPACITY | TIME RANGE | PRESSURE RANGE |
|---|---|---|---|
|
MSGL Reactors SS316 Reactors HASTELLOY Reactors |
100-1000 L 100-1000 L 250 L |
-25 to 200°C -25 to 180°C -25 to 200°C |
FV to 10 Kg/cm² FV to 30 Kg/cm² PV to 30 Kg/cm² |
|
SS-ETFE, SS316 Centrifuges |
24″ |
-20 to 120°C |
ATM |
|
Agitated Nutsche Filter & Dryer (SS316) |
250 L |
-25 to 180°C |
FV to 6 Kg/cm² |
|
Vacuum Tray Dryer (SS316) Fluidized Bed Dryer (SS316) |
24 Trays 50 L |
150°C 150°C |
FV to ATM ATM |
Clean Room Preparedness
Production Scale Clean Room Facility
| PLANNED KEY EQUIPMENT | CAPACITY | TIME RANGE | PRESSURE RANGE |
|---|---|---|---|
|
SS316 Reactors MSGL Reactors |
4KL 4KL |
-25 to 180°C -25 to 200°C |
FV to 6 Kg/cm² FV to 6 Kg/cm² |
|
SS-ETFE Centrifuges |
60″ |
-20 to 120°C |
ATM |
|
Rotary Cone Vacuum Dryer (Hastelloy) Tray Dryer (SS316) |
2KL 96 Trays |
150°C 150°C |
FV to ATM ATM |
Pilot Scale Clean Room Facility
| PLANNED KEY EQUIPMENT | CAPACITY | TIME RANGE | PRESSURE RANGE |
|---|---|---|---|
|
MSGL Reactors SS316 Reactors |
250 L 250 L |
-25 to 200°C -25 to 180°C |
FV to 6 Kg/cm² FV to 10 Kg/cm² |
|
SS-ETFE Centrifuges |
24″ |
-20 to 120°C |
ATM |
|
Rotary Cone Vacuum Dryer (Hastelloy) |
250 L |
150°C |
FV to ATM |
|
Air Jet Mill |
1 Kg/hr |
150°C |
ATM |
Key Features of Our CDMO Services
- API Development and Manufacturing: Soon we will focus on producing high-quality Active Pharmaceutical Ingredients (APIs). Our cutting–edge facility is already set up to produce APIs effectively and reliably.
- Process Development: We optimize manufacturing processes to increase efficiency and lower costs. Our goal is to provide reliable solutions that enhance productivity.
- Quality Control: We carry out full testing and quality assurance at each phase of production to guarantee that our products are effective and safe.
- Regulatory Compliance: Punagri is oriented towards achieving GMP and regulatory accreditations from various International Bodies, providing our customers with the assurance that all our operations meet the highest safety and quality standards.
Why Choose Punagri?
Punagri is a reputable CDMO pharma company in India because of our dedication to excellence. Our advanced technology, skilled team, and customer-centric approach make us a trusted partner for pharmaceutical companies worldwide.
We recognize the value of on-time delivery and quality consistency. With Punagri, customers can count on us for reliable CDMO services that advance their business objectives.
Get in Touch
Collaborate with Punagri for your CDMO requirements. Our committed team is here to help you get your pharmaceutical products to market quickly and effectively. Reach out to us today to learn more about how we can support your development and manufacturing needs.
Frequently Asked Questions
A CDMO offers contract services for API Intermediate development and manufacturing, enabling pharma businesses to lower costs, provide quality, and accelerate production.
Punagri follows strict global regulatory guidelines and conducts rigorous quality control at every stage to guarantee that our products are both safe and effective.
Punagri provides complete API Intermediate development, scalable production, and affordable solutions, with timely delivery and compliance with global standards.